《安东尼与克莉奥佩特拉》是莎士比亚于1607年左右编写的罗马悲剧，它是源于古罗马历史学家普鲁塔克的《希腊罗马名人传》。
戏剧讲述的是当时罗马的三大首领之一：安东尼因沉迷于埃及女王克莉奥佩特拉的美色而无暇于国家大事，终日与她在埃及厮混，天天醉生梦死。后来，罗马受到塞克斯特斯·庞贝的叛乱，海盗的入侵，东方帕提亚人的入侵以及安东尼妻子因向凯撒挑战失败而死的消息终于让他重新振作起来，毅然回到罗马，为祖国效力。安东尼遂因形势需要与屋大维和好，并娶其妹来巩固彼此的政治关系。这也让克莉奥佩特拉又伤心又愤怒。终于，各种战事和解消停后，安东尼迫不及待的回到了埃及女王身边。后来庞贝被杀，同僚莱皮德斯被废黜导致了最后安东尼和屋大维的两虎对峙。在海上对战中，安东尼不明智地跟随埃及女王逃跑而战败，最终伤心自刎，克莉奥佩特拉也终于看清屋大维的真面目，自杀身亡。
悲剧意义是深刻的、辩证的、多方面的，莎士比亚既肯定这种生死的爱情，又指出其中不纯的易碎的成分；既肯定他们现实观点的享受人生，又批判了他们爱情至上、放纵感情的生活态度，批判他们为了个人眼前利益而置国家兴亡于不顾，并提出许多有益的教训，如安东尼失败的原因，军人不应贪恋都市生活，人格尊严与道德荣誉比生命重要，强国的专横和弱国的悲哀，对民主自由政治的向往，以及对政治风云和人世沧桑的变化的慨叹等。
当安东尼在埃及首都亚历山大宫中耽溺于和克莉奥佩特拉的玩乐饮宴生活时，罗马帝国面对着塞克斯特斯·庞贝的叛乱、海盗的骚扰和东方帕提亚（安息）人的入侵。
形势紧急以及妻子芙尔维亚去世的消息，使安东尼心中重新唤起对国家的责任感，毅然回到罗马，同屋大维·凯撒及莱皮德斯聚首。安东尼和屋大维相互指责，经旁人劝解，渐趋和好。为了巩固同盟，安东尼同意娶屋大维之妹续弦。
消息传到亚历山大，克莉奥佩特拉怒不可遏，逼问信差，要了解新妇的容貌身材，是否能缠住安东尼的心。三巨头同庞贝达成妥协（公元前39年的米塞那协议），海盗归顺，安东尼派兵剿平了帕提亚（公元前38年）。
安东尼移驻雅典，其部下谋杀了庞贝；屋大维留驻罗马，找借口罢黜了懦弱的莱皮德斯（公元前36年）。这样，罗马帝国只剩下安东尼和屋大维两雄，相持相斥，为了专权，终至发展到必欲吞灭对方而后快。安东尼的后妻要去找哥哥劝和。她一走，安东尼立即回到克莉奥佩特拉的身旁。安、屋两军在希腊西岸的亚克兴对仗（公元前31年），安东尼固执地放弃陆上优势，选择在海上决战。
两支舰队一相遇，克莉奥佩特拉所在的船掉头逃遁，安东尼所乘旗舰尾随而去，安的舰队失去指挥而大败。安东尼回到埃及，对克莉奥佩特拉又是责怪，又是抚慰，企图重整旗鼓，强颜欢笑。屋大维率军追来，兵临城下。
安东尼的陆军一度小胜，但仅属回光返照，海军则不战而降，部下又纷纷倒戈。讹传克莉奥佩特拉已死，安东尼英雄末路，自刺未死。克莉奥佩特拉躲入反锁的墓室，和临死的安东尼诀别。屋大维设计稳住美人，打算活捉她带到罗马，在自己的凯旋游行中作为俘虏示众。克莉奥佩特拉佯作就范，暗中搞到尼罗河特产的剧毒小蛇，在最后一刻自螫而死，殉了情，也殉了国。时为公元前30年，安东尼终年52岁，克莉奥佩特拉39岁。
Antony and Cleopatra is a Roman tragedy written by Shakespeare around 1607. It originates from the Biographies of Greek and Roman Celebrities by the ancient Roman historian Plutarch.

The play is about one of the three leaders of Rome at that time: Anthony was too busy with national affairs because he was addicted to the beauty of Egyptian Queen Cleopatra, and he spent all day with her in Egypt, getting drunk every day. Later, Rome was rebelled by Seix Tex Pompey, invaded by pirates, invaded by the Oriental Parthia people, and the news that Anthony’s wife died because of her failure to challenge Caesar finally made him pick himself up again, and resolutely returned to Rome to serve the motherland. Anthony then reconciled with Udaiwa due to the situation and married his sister to consolidate their political relationship. This also made Cleopatra sad and angry. Finally, after various conflicts were resolved and reconciled, Anthony eagerly returned to the side of the Egyptian queen. Later, Pompeii was killed and his colleague Lepidus was deposed, leading to a final confrontation between Anthony and Octavian. In the battle at sea, Anthony unwisely fled with the Queen of Egypt and was defeated. Finally, he committed suicide. Cleo Petra finally saw Octavian’s true face and committed suicide.

The tragic significance is profound, dialectical, and multifaceted. Shakespeare not only affirms this love of life and death, but also points out its impure and fragile elements; They not only affirm their realistic views on enjoying life, but also criticize their attitude towards love and indulgence in emotions, criticize them for disregarding the rise and fall of the country for personal immediate interests, and propose many useful lessons, such as the reasons for Anthony’s failure, soldiers should not be greedy for urban life, personal dignity and moral honor are more important than life, the tyranny of a strong country and the sorrow of a weak country, and the yearning for democracy, freedom, and politics, And laments about the changes in the political landscape and the vicissitudes of life.

When Anthony indulged in playing and drinking with Cleopatra in Alexandria Palace, the List of historical capitals of Egypt, the Roman Empire faced the rebellion of Seix Tex Pompey, the harassment of pirates and the invasion of Parthia (Sabbath) people in the East.

The urgent situation and the news of the death of his wife, Sylvia, revived Anthony’s sense of responsibility for the country and resolutely returned to Rome, where his roommates, David Caesar and Lepides, gathered. Anthony and Octavian accused each other, but after being persuaded by others, they gradually reconciled. In order to consolidate the alliance, Anthony agreed to marry Octavian’s sister to renew his marriage.

When the news reached Alexander, Cleo Petra was furious and asked the messenger if he could get hold of Anthony’s heart if he wanted to know the appearance and figure of the bride. The three giants reached a compromise with Pompeii (the Misena Agreement in 39 BC), the pirates surrendered, and Antony sent troops to suppress Parthia (38 BC).

Anthony moved to Athens and his subordinates murdered Pompeii; Octavian stayed in Rome and used excuses to depose the cowardly Lepidus (36 BC). In this way, the Roman Empire was left with only Anthony and Octavian, opposing each other and ultimately developing to the point where they were determined to devour each other for the sake of dictatorship. Anthony’s stepwife is going to find her brother to reconcile. As soon as she left, Anthony immediately returned to Cleo Petra’s side. Antony stubbornly gave up his land superiority and chose to fight at sea in Actium on the west bank of Greece (31 BC).

As soon as the two fleets met, Cleopatra’s ship turned and fled, Anthony’s flag ship followed, and Ann’s fleet lost command and was defeated. When Anthony returned to Egypt, he blamed and comforted Cleopatra, trying to regroup and force a smile. Octavian led his army to pursue him, and the troops were approaching the city.

Anthony’s army briefly won, but it was only a comeback, while the navy surrendered without fighting, and his subordinates defected one after another. It is rumored that Cleopatra is dead, and Anthony’s hero is dead. Cleopatra hid in the locked tomb and said goodbye to Anthony who was dying. Octavian designed to stabilize the beauty and planned to capture her alive and bring her to Rome for public display as a prisoner in his triumphal parade. Cleopatra pretended to obey, and secretly got the highly poisonous snake of Nile specialty. At the last moment, she killed herself by stinging herself and died for love and country. It was 30 BC, Anthony was 52 years old, and Cleo Petra was 39 years old.

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